Controlling the L‐Asparaginase extraction and purification by the appropriate selection of polymer/salt‐based aqueous biphasic systems

BACKGROUND: L-Asparaginase (ASNase) is an important biopharmaceutical for the treatment of acute lymphoblastic leukemia (ALL); however, with some restrictions due to its high manufacturing costs. Aqueous biphasic systems (ABS) have been suggested as more economical platforms for the separation/purif...

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Bibliographic Details
Main Author: Magri, Agnes (author)
Other Authors: Pimenta, Marcela V. (author), Santos, João H. P. M. (author), Coutinho, João A. P. (author), Ventura, Sónia P. M. (author), Monteiro, Gisele (author), Yagui, Carlota O. R. (author), Pereira, Jorge F. B. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Enzymes
Aqueous biphasic systems (ABS)
Bioseparations
Liquid–liquid extraction
Purification
Separation
Online Access:http://hdl.handle.net/10773/28199
Country:Portugal
Oai:oai:ria.ua.pt:10773/28199

Internet

http://hdl.handle.net/10773/28199

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