HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E-coli by a similar mechanism of action

HIV-1 Vif protein protects viral replication in non-permissive cells by inducing degradation of APOBEC3G via ubiquitination and proteasomal pathway, although new studies indicate a putative role in Vif's direct inhibition of APOBEC3G. APOBEC3G is member o

Bibliographic Details
Main Author: Santa-Marta, Mariana (author)
Other Authors: da Silva, Frederico Aires (author), Fonseca, Ana Margarida (author), Rato, Sylvie (author), Goncalves, Joao (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Immunology
Online Access:http://hdl.handle.net/10451/21607
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21607
Description
Summary:HIV-1 Vif protein protects viral replication in non-permissive cells by inducing degradation of APOBEC3G via ubiquitination and proteasomal pathway, although new studies indicate a putative role in Vif's direct inhibition of APOBEC3G. APOBEC3G is member o

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