Nanoparticulate delivery system for insulin: Design, characterization and in vitro/in vivo bioactivity

Insulin-loaded alginate-dextran nanospheres were prepared by nanoemulsion dispersion followed by triggered in situ gelation. Nanospheres were characterized for mean size and distribution by laser diffraction spectroscopy and for shape by transmission electron microscopy. Insulin encapsulation effici...

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Bibliographic Details
Main Author: Reis, Catarina Pinto (author)
Other Authors: Ribeiro, António J. (author), Houng, Simone (author), Veiga, Francisco (author), Neufeld, Ronald J. (author)
Format: article
Language:eng
Published: 2007
Subjects:
Online Access:http://hdl.handle.net/10316/5859
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5859