Development and validation of an analytical method for the simultaneous determination of cocaine and its main metabolite, benzoylecgonine, in human hair by gas chromatography/mass spectrometry.
A new, simple and rapid procedure has been developed and validated for the determination of cocaine and its main metabolite, benzoylecgonine, in human hair samples. After extraction from within the hair matrix by a mixture of methanol/hydrochloric acid (2:1) at 65-C for 3 h, and sample cleanup by mi...
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| Other Authors: | , , , |
| Format: | article |
| Language: | eng |
| Published: |
2010
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| Online Access: | http://hdl.handle.net/10400.6/619 |
| Country: | Portugal |
| Oai: | oai:ubibliorum.ubi.pt:10400.6/619 |