pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal

The nucleotide sequences of the pncA genes within 55 multidrug-resistant pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates were determined. Fifty-three out of the 55 isolates were pyrazinamidase (PZase) negative. Four strains contained a

Bibliographic Details
Main Author: Portugal, I (author)
Other Authors: Barreiro, L (author), Moniz-Pereira, J (author), Brum, L (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21277
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21277
Description
Summary:The nucleotide sequences of the pncA genes within 55 multidrug-resistant pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates were determined. Fifty-three out of the 55 isolates were pyrazinamidase (PZase) negative. Four strains contained a