Pulmonary nodule segmentation in computed tomography with deep learning

Early detection of lung cancer is essential for treating the disease. Lung nodule segmentation systems can be used together with Computer-Aided Detection (CAD) systems, and help doctors diagnose and manage lung cancer. In this work, we create a lung nodule segmentation system based on deep learning....

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Bibliographic Details
Main Author: Gomes, João Henriques Oliveira (author)
Format: masterThesis
Language:eng
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10071/15479
Country:Portugal
Oai:oai:repositorio.iscte-iul.pt:10071/15479
Description
Summary:Early detection of lung cancer is essential for treating the disease. Lung nodule segmentation systems can be used together with Computer-Aided Detection (CAD) systems, and help doctors diagnose and manage lung cancer. In this work, we create a lung nodule segmentation system based on deep learning. Deep learning is a sub-field of machine learning responsible for state-of-the-art results in several segmentation datasets such as the PASCAL VOC 2012. Our model is a modified 3D U-Net, trained on the LIDC-IDRI dataset, using the intersection over union (IOU) loss function. We show our model works for multiple types of lung nodules. Our model achieves state-of-the-art performance on the LIDC test set, using nodules annotated by at least 3 radiologists and with a consensus truth of 50%.