Cloning, characterisation and expression of the apolipoprotein A-I gene in the sea bream (Sparus aurata)

A full length cDNA clone representing apolipoprotein A-I was isolated from a sea bream (Sparus aurata) liver library. The clone encodes a 261 amino acid protein which shows highest amino acid identity (38%) with salmon apolipoprotein A-I. Northern blot analysis showed strong expression of a 1.4 kb t...

Full description

Bibliographic Details
Main Author: Llewellyn, Lynda (author)
Other Authors: Ramsurn, Vimi P. (author), Wigham, Trevor (author), Sweeney, Glen E. (author), Power, Deborah (author)
Format: article
Language:eng
Published: 2014
Subjects:
Apolipoprotein A-I
Teleost fish
Triiodothyronine (T3)
Sea bream
Sparus aurata
Online Access:http://hdl.handle.net/10400.1/5456
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/5456
Description
Summary:A full length cDNA clone representing apolipoprotein A-I was isolated from a sea bream (Sparus aurata) liver library. The clone encodes a 261 amino acid protein which shows highest amino acid identity (38%) with salmon apolipoprotein A-I. Northern blot analysis showed strong expression of a 1.4 kb transcript in liver with lower expression in intestine. Expression of apolipoprotein A-I in intestine was markedly reduced by treatment with triiodothyronine (T3). ß 1998 Elsevier Science B.V. All rights reserved.

Similar Items