Signal transduction pathways involving the hypertension-related WNK1 and WNK4 protein kinases

The genes WNK1 and WNK4 belong to the subfamily of WNK protein kinases and their mutation causes pseudohypoaldosteronism type II, a rare familial form of hypertension with hyperkalemia and hypercalciuria. The molecular mechanisms underlying this condition involve the regulation of renal electrolyte...

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Bibliographic Details
Main Author: Mendes, Ana Isabel (author)
Format: doctoralThesis
Language:eng
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10400.18/103
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/103