Signal transduction pathways involving the hypertension-related WNK1 and WNK4 protein kinases
The genes WNK1 and WNK4 belong to the subfamily of WNK protein kinases and their mutation causes pseudohypoaldosteronism type II, a rare familial form of hypertension with hyperkalemia and hypercalciuria. The molecular mechanisms underlying this condition involve the regulation of renal electrolyte...
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Format: | doctoralThesis |
Language: | eng |
Published: |
2011
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Online Access: | http://hdl.handle.net/10400.18/103 |
Country: | Portugal |
Oai: | oai:repositorio.insa.pt:10400.18/103 |