Micronucleus and H2AX phosphorylation assessment of silica-coated iron oxide nanoparticles in human neuronal cells

As clinically approved metal oxide nanoparticles, iron oxide nanoparticles (ION) hold immense potential in a vast variety of applications in various fields of biomedicine and biotechnology. With the increase in ION usage, particularly in diagnostics and therapeutics, concerns regarding their interac...

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Detalhes bibliográficos
Autor principal: Sánchez-Flores, Maria (author)
Outros Autores: Valdiglesias, Vanessa (author), Kiliç, Gozde (author), Costa, Carla (author), Fernandez-Bertolez, Natalia (author), Costa, Solange (author), Teixeira, João Paulo (author), Pasaro, Eduardo (author), Laffon, Blanca (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2016
Assuntos:
Iron Oxide
Nanomaterials
Human Neuronal Cells
Nanoparticles
Genotoxicidade Ambiental
Texto completo:http://hdl.handle.net/10400.18/3649
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3649
Descrição
Resumo:As clinically approved metal oxide nanoparticles, iron oxide nanoparticles (ION) hold immense potential in a vast variety of applications in various fields of biomedicine and biotechnology. With the increase in ION usage, particularly in diagnostics and therapeutics, concerns regarding their interactions with cellular components and possible deleterious effects are also growing.

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