Photonic modulation of epidermal growth factor receptor halts receptor activation and cancer cell migration

Epidermal Growth Factor Receptor (EGFR) plays a key role in regulating cell survival, proliferation and migration, and its overexpression and activation has been correlated with cancer progression. Cancer therapies targeting EGFR have been applied in the clinic with some success. We show, by confoca...

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Bibliographic Details
Main Author: Botelho, Cláudia M. (author)
Other Authors: Gonçalves, O. (author), Marques, R. (author), Thiagarajan, V. (author), Vorum, H. (author), Gomes, A. (author), Petersen-Neves, T. (author)
Format: article
Language:eng
Published: 2018
Subjects:
arrest cancer cell migration
EGF
EGFR
metastasis
photonic cancer therapy
protein photochemistry
Science & Technology
Online Access:http://hdl.handle.net/1822/56359
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/56359

Internet

http://hdl.handle.net/1822/56359

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