Dehydrodipeptide hydrogelators containing naproxen N-capped tryptophan: self-assembly, hydrogel characterization, and evaluation as potential drug nanocarriers

In this work, we introduce dipeptides containing tryptophan N-capped with the nonsteroidal anti-inflammatory drug naproxen and C-terminal dehydroamino acids, dehydrophenylalanine (ΔPhe), dehydroaminobutyric acid (ΔAbu), and dehydroalanine (ΔAla) as efficacious protease resistant hydrogelators. Optim...

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Bibliographic Details
Main Author: Vilaça, Helena (author)
Other Authors: Hortelão, Ana C. L. (author), Castanheira, Elisabete M. S. (author), Queiroz, Maria João R. P. (author), Hilliou, L. (author), Hamley, Ian W. (author), Martins, José A (author), Ferreira, Paula M. T. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Peptide
Hydrogel
Ciências Naturais::Ciências Químicas
Science & Technology
Online Access:http://hdl.handle.net/1822/38228
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/38228

Internet

http://hdl.handle.net/1822/38228

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