Mgp expression and accumulation in heart and kidney of turbot (Scophthalmus maximus)

Matrix γ-carboxyglutamic acid (Gla) protein (Mgp) is a vitamin K-dependent protein normally found associated with the organic matrix of cartilage and bone in vivo. After the discovery of Mgp in various soft tissues, this protein was proposed to act as a local inhibitor of mineralization although its...

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Detalhes bibliográficos
Autor principal: Roberto, Vania Palma (author)
Outros Autores: Cavaco, S. (author), Simes, D (author), Gavaia, Paulo J. (author), Cancela, Leonor (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2014
Texto completo:http://hdl.handle.net/10400.1/4386
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/4386
Descrição
Resumo:Matrix γ-carboxyglutamic acid (Gla) protein (Mgp) is a vitamin K-dependent protein normally found associated with the organic matrix of cartilage and bone in vivo. After the discovery of Mgp in various soft tissues, this protein was proposed to act as a local inhibitor of mineralization although its molecular mechanisms of action remain incompletely understood.