Proving the suitability of magnetoelectric stimuli for tissue engineering applications

A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast...

Full description

Bibliographic Details
Main Author: Ribeiro, C. (author)
Other Authors: Correia, Vítor Manuel Gomes (author), Martins, P. (author), Gama, F. M. (author), Lanceros-Méndez, S. (author)
Format: article
Language:eng
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/1822/40151
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/40151
Description
Summary:A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli.