Acute Kidney Injury Associated with COVID-19 Infection: a Case Report

SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney bio...

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Bibliographic Details
Main Author: Duarte, T (author)
Other Authors: Caeiro, F (author), Góis, M (author), Matos, A (author), Viana, H (author), Vieira, C (author), Paulos, J (author), Paixão, P (author), Matos, B (author), Germano, N (author), Nolasco, F (author)
Format: article
Language:eng
Published: 2021
Subjects:
HCC UCI
HCC NEF
HCC ANPAT
Acute Kidney Injury
COVID-19
Kidney Biopsy
Online Access:http://hdl.handle.net/10400.17/3910
Country:Portugal
Oai:oai:repositorio.chlc.min-saude.pt:10400.17/3910
Description
Summary:SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.

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