VCAM1 modulation on endothelial cells – implications for vasculopathy in sickle cell anemia

Sickle cell anemia (SCA) is a highly heterogeneous and multifactorial-like monogenic disease that arises from homozygosity for the c.20A>T mutation in the HBB gene. Vascular disease is systemic in SCA, with profound effects in organs like the brain, where stroke is the most severe end of the cere...

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Detalhes bibliográficos
Autor principal: Silva, Marisa (author)
Outros Autores: Vargas, Sofia (author), Coelho, Andreia (author), Lavinha, João (author), Faustino, Paula (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2020
Assuntos:
Sickle Cell Anemia
Drepanocitose
Anemia das Células Falciformes
AVC
Medicina personalizada
VCAM1
Vasculopatia cerebral
Hemoglobinopatias
Doenças Genéticas
Doenças Raras
Texto completo:http://hdl.handle.net/10400.18/6724
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6724

Texto Completo

http://hdl.handle.net/10400.18/6724

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