Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade extracellular matrix (ECM), thus assisting invasion. Upregulation of MMPs, frequently reported in gliomas, is associated with aggressive behavior. WNK2 is a tumor suppressor gene expressed in normal brain, and silenced by promoter...

ver descrição completa

Detalhes bibliográficos
Autor principal: Costa, Angela Margarida (author)
Outros Autores: Pinto, Filipe (author), Martinho, Olga (author), Oliveira, Maria José (author), Jordan, Peter (author), Reis, R. M. (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
WNK2
MMP2
JNK
Gliomas
Invasion
Science & Technology
Texto completo:http://hdl.handle.net/1822/32853
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32853

Texto Completo

http://hdl.handle.net/1822/32853

Registos relacionados