An improved evolutionary algorithm-based framework for identifying in silico metabolic engineering targets

In metabolic engineering problems, due to the complexity of metabolic networks, it is often difficult to identify a priori which genetic manipulations will originate a given desired phenotype. Genome-scale metabolic models, available for several microorganisms, can be used to simulate the metabolic...

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Detalhes bibliográficos
Autor principal: Rocha, I. (author)
Outros Autores: Rocha, Miguel (author), Ferreira, Eugénio C. (author), Patil, Kiran Raosaheb (author), Nielsen, Jens (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2006
Texto completo:https://hdl.handle.net/1822/5916
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/5916