An improved evolutionary algorithm-based framework for identifying in silico metabolic engineering targets
In metabolic engineering problems, due to the complexity of metabolic networks, it is often difficult to identify a priori which genetic manipulations will originate a given desired phenotype. Genome-scale metabolic models, available for several microorganisms, can be used to simulate the metabolic...
Main Author: | |
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Other Authors: | , , , |
Format: | conferenceObject |
Language: | eng |
Published: |
2006
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Online Access: | https://hdl.handle.net/1822/5916 |
Country: | Portugal |
Oai: | oai:repositorium.sdum.uminho.pt:1822/5916 |