Relevance of Plasma Homocysteine and Methylenetetrahydrofolate Reductase 677TT Genotype in Sickle Cell Disease

We evaluated the relevance of plasma homocysteine (HC) and the TT genotype of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in sickle cell disease (SCD) and associated vaso-occlusive crisis (VOC) and ischemic stroke (IS). We identified in Embase and Medline 22 studie...

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Bibliographic Details
Main Author: Ames, Paul R.J. (author)
Other Authors: Arcaro, Alessia (author), Caruso, Matilde (author), Graf, Maria (author), Marottoli, Vincenzo (author), Gentile, Fabrizio (author)
Format: review
Language:eng
Published: 2022
Subjects:
homocysteine
ischemic stroke
methylenetetrahydrofolate reductase
MTHFR TT genotype
sickle cell disease
vaso-occlusive crisis
Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry
Online Access:http://hdl.handle.net/10362/146696
Country:Portugal
Oai:oai:run.unl.pt:10362/146696

Internet

http://hdl.handle.net/10362/146696

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