Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta 1-induced apoptosis in rat hepatocytes

Ursodeoxycholic acid (UDCA) inhibits classical mitochondrial pathways of apoptosis by either directly stabiliz* mitochondrial membranes or modulating specific upstream targets. Furthermore, UDCA regulates apoptosis-related genes from transforming growth f

Bibliographic Details
Main Author: Sola, S (author)
Other Authors: Amaral, J (author), Castro, RE (author), Ramalho, RM (author), Borralho, PM (author), Kren, BT (author), Tanaka, H (author), Steer, CJ (author), Rodrigues, CMP (author)
Format: article
Language:eng
Published: 2015
Subjects:
Gastroenterology & Hepatology
Online Access:http://hdl.handle.net/10451/21504
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21504

Internet

http://hdl.handle.net/10451/21504

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