Mitochondrial dynamics and quality control in Huntington's disease
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by polyglutamine expansion mutations in the huntingtin protein. Despite its ubiquitous distribution, expression of mutant huntingtin (mHtt) is particularly detrimental to medium spiny neurons within the striatum. Mitoch...
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| Other Authors: | , , , , |
| Format: | article |
| Language: | eng |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://repositorio-aberto.up.pt/handle/10216/104640 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/104640 |