Identification of an IRES element in the human mTOR transcript that insures its expression and function during inhibition of global translation
Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals from the cellular nutrient- and energy-status, acting namely on the protein synthesis machinery. Deregulation of mTOR signaling is implicated in major diseases, such as cancer, mainly due to its role...
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| Formato: | conferenceObject |
| Idioma: | eng |
| Publicado em: |
2017
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| Texto completo: | http://hdl.handle.net/10400.18/3656 |
| País: | Portugal |
| Oai: | oai:repositorio.insa.pt:10400.18/3656 |