Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system

In the present work, we used a novel albumin-associated lipoplex formulation, containing the cationic lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (EPOPC) and cholesterol (Chol), to evaluate the antitumoral efficacy of two gene therapy strategies: immuno-gene therapy, mediated by IL-1...

Full description

Bibliographic Details
Main Author: Faneca, H. (author)
Other Authors: Cabrita, A. S. (author), Simões, S. (author), Lima, M. C. Pedroso de (author)
Format: article
Language:eng
Published: 2007
Subjects:
Cancer gene therapy
"Suicide" gene therapy
Immunotherapy
Gene delivery
Cationic liposomes
Transfection
Online Access:http://hdl.handle.net/10316/4720
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/4720

Internet

http://hdl.handle.net/10316/4720

Similar Items