Nonsense-Mediated mRNA decay in development, stress and cancer

Nonsense-mediated mRNA decay (NMD) is a well characterized eukaryotic mRNA degradation pathway, responsible for the identification and degradation of transcripts harboring translation termination codons in premature contexts. Transcriptome-wide studies revealed that NMD is not only an mRNA surveilla...

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Bibliographic Details
Main Author: Fernandes, Rafael (author)
Other Authors: Nogueira, Gonçalo (author), da Costa, Paulo J. (author), Pinto, Francisco (author), Romão, Luísa (author)
Format: article
Language:eng
Published: 2020
Subjects:
Nonsense-mediated mRNA Decay
Gene Expression Regulation
Human Disease
Integrated Stress Response
Tumorigenesis
Unfolded Protein Response
mRNA Surveillance
Genómica Funcional e Estrutural
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/6544
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6544

Internet

http://hdl.handle.net/10400.18/6544

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