Structure–activity relationships in hydroxy-2,3-diarylxanthone antioxidants. Fast kinetics spectroscopy as a tool to evaluate the potential for antioxidant activity in biological systems

A structure–activity relationship has been established for eight hydroxy-2,3-diarylxanthones (XH) bearing hydroxy groups on the two aryl rings. One-electron oxidation by superoxide radical-anions (ΣO2 -) and ΣTrp radicals as well as reaction with ΣCCl3O2 and ΣCHCl2O2 radicals demonstrates that two O...

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Bibliographic Details
Main Author: Santos, Clementina M.M. (author)
Other Authors: Silva, Artur (author), Filipe, Paulo (author), Santus, René (author), Patterson, Larry K. (author), Maziére, Jean-Claude (author), Cavaleiro, José (author), Morlière, Patrice (author)
Format: article
Language:eng
Published: 2011
Subjects:
Pulse-radiolysis
Aqueous solution
Radical-anions
Rate constants
Vitamin-E
LDL
Online Access:http://hdl.handle.net/10198/6255
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/6255

Internet

http://hdl.handle.net/10198/6255

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