Spectroscopic characterization of a coumarin-labelled therapeutic tetrapeptide

The present work describes the synthesis of the tetrapeptide H-Ala-Ala-Pro-Val-NH2 (AAPV), an important inhibitor of the enzyme human neutrophil elastase, labelled at the C-terminus with a 7-methoxycoumarinyl moiety. Photophysical studies were made with spectroscopic characterization by UV-vis and f...

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Bibliographic Details
Main Author: Santos, F. C. (author)
Other Authors: Gonçalves, M. Sameiro T. (author), Costa, Susana P. G. (author)
Format: conferencePaper
Language:eng
Published: 2015
Subjects:
AAPV
peptide
photorelease
photocleavable protecting groups
Ciências Naturais::Ciências Químicas
Online Access:http://hdl.handle.net/1822/53760
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/53760

Internet

http://hdl.handle.net/1822/53760

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