SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells

BACKGROUND: Basal-like breast cancer (BLBC) is a poor prognosis subgroup of triple-negative carcinomas that still lack specific target therapies and accurate biomarkers for treatment selection. P-cadherin is frequently overexpressed in these tumors, promoting cell invasion, stem cell activity and tu...

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Bibliographic Details
Main Author: Ribeiro, AS (author)
Other Authors: Nobre, AR (author), Mendes, N (author), Almeida, J (author), Vieira, AF (author), Sousa, B (author), Carvalho, F (author), Monteiro, J (author), Polónia, A (author), Fonseca, M (author), Sanches, J (author), Santos, N (author), Seruca, R (author), Paredes, J (author)
Format: article
Language:eng
Published: 2018
Subjects:
Basal-like breast cancer
Dasatinib
P-cadherin
Src family kinase
Online Access:https://hdl.handle.net/10216/126481
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/126481

Internet

https://hdl.handle.net/10216/126481

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