Preparation and biological evaluation of ethionamide-mesoporous silicon nanoparticles against Mycobacterium tuberculosis

Ethionamide (ETH) is an important second-line antituberculosis drug used for the treatment of patients infected with multidrug-resistant Mycobacterium tuberculosis. Recently, we reported that the loading of ETH into thermally carbonized-porous silicon (TCPSi) nanoparticles enhanced the solubility an...

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Bibliographic Details
Main Author: Vale, Nuno (author)
Other Authors: Correia, Alexandra (author), Silva, Sara (author), Figueiredo, Patrícia (author), Mäkilä, , Ermei (author), Salonen, Jarno (author), Hirvonen, Jouni (author), Pedrosa, Jorge (author), Santos Hélder A. (author), Fraga, Alexandra (author)
Format: article
Language:eng
Published: 2017
Subjects:
Ethionamide
Porous silicon nanoparticles
Mycobacterium tuberculosis
Strain H37Rv
MIC50
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/49052
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/49052

Internet

http://hdl.handle.net/1822/49052

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