Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac

Aminocarbonyloxymethyl ester prodrugs are known to undergo rearrangement in aqueous solutions to form the corresponding N-acylamine side product via an 0 - N intramolecular acyl transfer from the carbamate conjugate base. Novel aminocarbonyloxymethyl esters of diclofenac and flufenamic acid containi...

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Bibliographic Details
Main Author: Ribeiro, Lina (author)
Other Authors: Silva, Nuno (author), Iley, Jim (author), Rautio, Jarkko (author), Jarvinen, Tomi (author), Mota-Filipe, Helder (author), Moreira, Rui (author), Mendes, Eduarda (author)
Format: article
Language:eng
Published: 2015
Subjects:
Chemistry, Medicinal
Chemistry, Multidisciplinary
Pharmacology & Pharmacy
Online Access:http://hdl.handle.net/10451/21593
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21593

Internet

http://hdl.handle.net/10451/21593

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