Molecular basis of bilirubin-induced neurotoxicity
Unconjugated bilirubin (UCB), at slightly elevated unbound concentrations, is toxic to astrocytes and neurons, damaging mitochondria (causing impaired energy metabolism and apoptosis) and plasma membranes (causing oxidative damage and disrupting transport of neurotransmitters). Accumulation of UCB i...
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| Other Authors: | , , |
| Format: | article |
| Language: | eng |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10451/21148 |
| Country: | Portugal |
| Oai: | oai:repositorio.ul.pt:10451/21148 |