The contribution of CK2 and spleen tyrosine kinase (SYK) to CFTR trafficking and PKA-induced activity

Previously, the pleiotropic “master kinase” casein kinase 2 (CK2) was shown to interact with CFTR, the protein responsible for cystic fibrosis (CF). Moreover, CK2 inhibition abolished CFTR conductance in cell-attached membrane patches, native epithelial ducts, and Xenopus oocytes. CFTR possesses two...

ver descrição completa

Detalhes bibliográficos
Autor principal: Luz, Simão (author)
Outros Autores: Kongsuphol, Patthara (author), Mendes, Ana Isabel (author), Romeiras, Francisco (author), Sousa, Marisa (author), Schreiber, Rainer (author), Matos, Paulo (author), Jordan, Peter (author), Mehta, Anil (author), Amaral, Margarida D. (author), Kunzelmann, Karl (author), Farinha, Carlos M. (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Vias de Transdução de Sinal e Patologias Associadas
Cystic Fibrosis
Syk
Casein Kinase
Texto completo:http://hdl.handle.net/10400.18/907
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/907

Texto Completo

http://hdl.handle.net/10400.18/907

Registos relacionados