Importance of TP53 codon 72 and intron 3 duplication 16bp polymorphisms in prediction of susceptibility on breast cancer

Background: TP53 is one of major tumour suppressor genes being essential in preservation of genome integrity. Two very common polymorphisms have been demonstrated to contribute to cancer susceptibility and tumour behaviour. The purpose of this study was to evaluate the role of Arg72Pro and PIN3 Ins1...

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Bibliographic Details
Main Author: Costa, Sandra (author)
Other Authors: Pinto, Daniela (author), Pereira, Deolinda (author), Rodrigues, Helena (author), Cameselle-Teijeiro, Jorge (author), Medeiros, Rui (author), Schmitt, Fernando (author)
Format: article
Language:eng
Published: 2008
Subjects:
Adult
Aged
Breast Neoplasms
Case-Control Studies
Codon
DNA, Neoplasm
Female
Genetic Predisposition to Disease
Humans
Introns
Lymphatic Metastasis
Middle Aged
Polymorphism, Genetic
Genes, p53
Science & Technology
Online Access:http://hdl.handle.net/1822/58830
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/58830

Internet

http://hdl.handle.net/1822/58830

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