Curcumin encapsulated into methoxy Poly(Ethylene Glycol) Poly(ε-Caprolactone) nanoparticles increases cellular uptake and neuroprotective effect in glioma cells

Curcumin is a natural polyphenolic compound isolated from turmeric (Curcuma longa) with well-demonstrated neuroprotective and anticancer activities. Although curcumin is safe even at high doses in humans, it exhibits poor bioavailability, mainly due to poor absorption, fast metabolism, and rapid sys...

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Detalhes bibliográficos
Autor principal: Gregory, Marslin (author)
Outros Autores: Sarmento, Bruno Filipe Carmelino Cardoso (author), Martins, José Alberto Ribeiro (author), Silva, Carlos Jorge Ribeiro (author), Sárria, Marisa Passos (author), Gomes, Andreia (author), Coutinho, Olga Pereira (author), Dias, Alberto Carlos Pires (author), Franklin, Gregory (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
curcumin
PEGylated nanoparticles
neuroprotection
cellular uptake
zebrafish
Engenharia e Tecnologia::Nanotecnologia
Science & Technology
Texto completo:http://hdl.handle.net/1822/51218
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/51218

Texto Completo

http://hdl.handle.net/1822/51218

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