Curcumin encapsulated into methoxy Poly(Ethylene Glycol) Poly(ε-Caprolactone) nanoparticles increases cellular uptake and neuroprotective effect in glioma cells

Curcumin is a natural polyphenolic compound isolated from turmeric (Curcuma longa) with well-demonstrated neuroprotective and anticancer activities. Although curcumin is safe even at high doses in humans, it exhibits poor bioavailability, mainly due to poor absorption, fast metabolism, and rapid sys...

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Bibliographic Details
Main Author: Gregory, Marslin (author)
Other Authors: Sarmento, Bruno Filipe Carmelino Cardoso (author), Martins, José Alberto Ribeiro (author), Silva, Carlos Jorge Ribeiro (author), Sárria, Marisa Passos (author), Gomes, Andreia (author), Coutinho, Olga Pereira (author), Dias, Alberto Carlos Pires (author), Franklin, Gregory (author)
Format: article
Language:eng
Published: 2017
Subjects:
curcumin
PEGylated nanoparticles
neuroprotection
cellular uptake
zebrafish
Engenharia e Tecnologia::Nanotecnologia
Science & Technology
Online Access:http://hdl.handle.net/1822/51218
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/51218

Internet

http://hdl.handle.net/1822/51218

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