Leber’s hereditary optic neuropathy – Molecular study of 540 Portuguese patients

Leber's hereditary optic neuropathy (LHON) is a maternal hereditary disease that causes blindness due to optic atrophy, with typical onset during the second or third decade of life and affects predominantly males. The primary etiological factor relates to mutations in the mitochondrial genome....

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Bibliographic Details
Main Author: Esteves, Sofia (author)
Other Authors: Nogueira, Célia (author), Evangelista, Teresinha (author), Encarnação, Marisa (author), Teixeira, Marco (author), Neiva, Raquel (author), Pereira, Cristina (author), Vilarinho, Laura (author)
Format: article
Language:eng
Published: 2013
Subjects:
LHON
Doenças Genéticas
Optic Atrophy
Mitochondrial DNA
Leber Disease
Online Access:http://hdl.handle.net/10400.18/1170
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1170

Internet

http://hdl.handle.net/10400.18/1170

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