Lower NPAS3 expression during the later stages of abnormal lung development in rat congenital diaphragmatic hernia

Purpose Congenital diaphragmatic hernia (CDH) is characterized by a developmental defect in the diaphragm, pulmonary hypoplasia and pulmonary hypertension. NPAS3 is a PAS domain transcription factor regulating Drosophila tracheogenesis. NPAS3 null mice develop pulmonary hypoplasia in utero and die a...

Full description

Bibliographic Details
Main Author: Terra, Patrícia Daniela Pereira (author)
Other Authors: Kholdebarin, Ramin (author), Higgins, Meghan (author), Iwasiow, Barbara M. (author), Correia-Pinto, Jorge (author), Keijzer, Richard (author)
Format: article
Language:eng
Published: 2015
Subjects:
Congenital diaphragmatic hernia
Pulmonary hypoplasia
Lung development
Nitrofen
NPAS3
Ciências Médicas::Medicina Clínica
Online Access:http://hdl.handle.net/1822/40437
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/40437

Internet

http://hdl.handle.net/1822/40437

Similar Items