Molecular dynamics simulations of T-2410 and T-2429 HIV fusion inhibitors interacting with model membranes: Insight into peptide behavior, structure and dynamics

T-2410 and T-2429 are HIV fusion inhibitor peptides (FI) designed to present a higher efficiency even against HIV strains that developed resistance against other FIs. Similar peptides were shown to interact with model membranes both in the liquid disordered phase and in the liquid ordered state. Tho...

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Bibliographic Details
Main Author: Mavioso, I. C. V. C. (author)
Other Authors: de Andrade, V. C. R. (author), Palace Carvalho, A. J. (author), Martins do Canto, A. M. T. (author)
Format: article
Language:por
Published: 2018
Subjects:
AIDS
HIV fusion inhibitor
Lipid bilayer
T-2410
T-2429
Lipid-peptide interaction
Molecular dynamics
Online Access:http://hdl.handle.net/10174/22488
Country:Portugal
Oai:oai:dspace.uevora.pt:10174/22488

Internet

http://hdl.handle.net/10174/22488

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