A role for the small GTPases RAC1 and RAC1b in the modulation of NIS expression: potentiation of therapy with radioactive iodine in differentiated thyroid carcinoma

Introduction or Background: The Sodium Iodide Symporter (NIS) is responsible for active transport of iodide into thyroid follicular cells. The retention of its functional expression in most of the well-differentiated thyroid carcinomas (DTCs) enables the use of radioactive iodine (RAI) for treatment...

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Bibliographic Details
Main Author: Faria, Márcia (author)
Other Authors: Félix, Daniela (author), Domingues, Rita (author), Bugalho, Maria J. (author), Matos, Paulo (author), Silva, Ana L. (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Thyroid Cancer
RAC1b
NIS
Vias de Transdução de Sinal e Patologias Associadas
Online Access:http://hdl.handle.net/10400.18/6700
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6700

Internet

http://hdl.handle.net/10400.18/6700

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