Human Argonaute 1 5’ untranslated region can mediate cap-independent translation initiation via an internal ribosome entry site

Argonaute proteins (AGOs) are essential effectors in RNA-mediated gene silencing pathways. There are eight AGO-like proteins in human cells, grouped in two families: the eIF2C/AGO subfamily and the PIWI subfamily. The eIF2C1 gene encodes AGO1, a member of the former subfamily, that is ubiquitously e...

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Bibliographic Details
Main Author: Lacerda, Rafaela (author)
Other Authors: Marques-Ramos, Ana (author), Teixeira, Alexandre (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2015
Subjects:
Genómica Funcional
Argonaute Proteins (AGOs)
mRNA Translation
Internal Ribosome Entry Site (IRES)
Untranslated Region (UTR)
Online Access:http://hdl.handle.net/10400.18/2717
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2717

Internet

http://hdl.handle.net/10400.18/2717

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