Exploring the gap between dynamic and constraint-based models of metabolism

Systems biology provides new approaches for metabolic engineering through the development of models and methods for simulation and optimization of microbial metabolism. Here we explore the relationship between two modeling frameworks in common use namely, dynamic models with kinetic rate laws and co...

Full description

Bibliographic Details
Main Author: Machado, C. D. (author)
Other Authors: Costa, Rafael S. (author), Ferreira, Eugénio C. (author), Rocha, I. (author), Tidor, Bruce (author)
Format: article
Language:eng
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/1822/22325
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/22325