Therapeutic antisense oligonucleotides against cancer: Hurdling to the clinic
Under clinical development since the early 90's and with two successfully approved drugs (Fomivirsen and Mipomersen), oligonucleotide-based therapeutics has not yet delivered a clinical drug to the market in the cancer field. Whilst many pre-clinical data has been generated, a lack of understan...
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| Format: | article |
| Language: | eng |
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2014
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| Online Access: | https://hdl.handle.net/10216/120730 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/120730 |