The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids

The posttranslational modification of carboxy-terminal tails of tubulin plays an important role in the regulation of the microtubule cytoskeleton. Enzymes responsible for deglutamylating tubulin have been discovered within a novel family of mammalian cytosolic carboxypeptidases. The discovery of the...

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Bibliographic Details
Main Author: Tort, Olivia (author)
Other Authors: Tanco, Sebastián (author), Rocha, Cecilia (author), Bièche, Ivan (author), Seixas, Cecilia (author), Bosc, Christophe (author), Andrieux, Annie (author), Moutin, Marie Jo (author), Avilés, Francesc Xavier (author), Lorenzo, Julia (author), Janke, Carsten (author)
Format: article
Language:eng
Published: 2018
Subjects:
Online Access:https://doi.org/10.1091/mbc.E14-06-1072
Country:Portugal
Oai:oai:run.unl.pt:10362/40319