Cholinium-based ionic liquids as bioinspired hydrotropes to tackle solubility challenges in drug formulation

Hydrotropy is a well-established strategy to enhance the aqueous solubility of hydrophobic drugs, facilitating their formulation for oral and dermal delivery. However, most hydrotropes studied so far possess toxicity issues and are inefficient, with large amounts being needed to achieve significant...

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Bibliographic Details
Main Author: Sintra, Tânia E. (author)
Other Authors: Abranches, Dinis O. (author), Benfica, Jordana (author), Soares, Bruna P. (author), Ventura, Sónia P. M. (author), Coutinho, João A. P. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Hydrotropy
BCS Class II drugs
Ionic liquids
Drug formulation
Bioavailability
Choline
Ibuprofen
Naproxen
Online Access:http://hdl.handle.net/10773/33324
Country:Portugal
Oai:oai:ria.ua.pt:10773/33324

Internet

http://hdl.handle.net/10773/33324

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