Lipid-based Nanocarriers for siRNA Delivery: Challenges, Strategies and the Lessons Learned from the DODAX: MO Liposomal System

The possibility of using the RNA interference (RNAi) mechanisms in gene therapy was one of the scientific breakthroughs of the last century. Despite the extraordinary therapeutic potential of this approach, the need for an efficient gene carrier is hampering the translation of the RNAi technology to...

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Detalhes bibliográficos
Autor principal: Oliveira, Ana C. N. (author)
Outros Autores: Fernandes, Joana (author), Gonçalves, Anabela (author), Andreia C. Gomes (author), Real Oliveira, M. Elisabete C.D. (author), Gomes, Andreia C (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Cationic liposomes
monoolein
siRNA delivery
DODAB
DODAC
PEGylation
Science & Technology
Texto completo:http://hdl.handle.net/1822/55931
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/55931

Texto Completo

http://hdl.handle.net/1822/55931

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