Bis-indolyl benzenoids, hydroxypyrrolidine derivatives and other constituents from cultures of the marine sponge-associated fungus aspergillus candidus KUFA0062

A previously unreported bis-indolyl benzenoid, candidusin D (2e) and a new hydroxypyrrolidine alkaloid, preussin C (5b) were isolated together with fourteen previously described compounds: palmitic acid, clionasterol, ergosterol 5,8-endoperoxides, chrysophanic acid (1a), emodin (1b), six bis-indolyl...

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Bibliographic Details
Main Author: Buttachon S. (author)
Other Authors: Ramos A.A. (author), Inácio Â. (author), Dethoup T. (author), Gales L. (author), Lee M. (author), Costa P.M. (author), Silva A.M.S. (author), Sekeroglu N. (author), Rocha E. (author), Pinto M.M.M. (author), Pereira J.A. (author), Kijjoa A. (author)
Format: article
Language:eng
Published: 2018
Subjects:
2'' oxoasterriquinol D methyl ether
3,6 dibenzylpiperazine 2,5 dione
4 (acetylamino)benzoic acid
antibiotic agent
asterriquinol D dimethyl ether
benzene derivative
benzoic acid
bis indolyl benzenoid
candidusin D
chrysophanic acid
colistin
doxorubicin
fungal extract
kumbicin A
kumbicin B
kumbicin D
oxacillin
petromurin C
preussin
preussin C
pyrrolidine derivative
unclassified drug
vancomycin
anisomycin
antiinfective agent
antineoplastic agent
terphenyl derivative
A-375 cell line
A-549 cell line
antibacterial activity
antineoplastic activity
Article
Aspergillus candidus
Aspergillus candidus KUFA 0062
biofilm
cell viability
controlled study
drug cytotoxicity
drug identification
drug isolation
drug potentiation
Enterococcus faecalis
Escherichia coli
fungal strain
fungus culture
HCT 116 cell line
Hep-G2 cell line
HT-29 cell line
human
human cell
IC50
in vitro study
MCF-7 cell line
methicillin resistant Staphylococcus aureus
minimum bactericidal concentration
minimum inhibitory concentration
nonhuman
Pseudomonas aeruginosa
Staphylococcus aureus
T98G cell line
U-251MG cell line
vancomycin resistant Enterococcus
analogs and derivatives
animal
antibiotic resistance
Aspergillus
bacterium
chemistry
drug effect
isolation and purification
microbial sensitivity test
microbiology
sponge (Porifera)
tumor cell line
Animals
Anisomycin
Anti-Bacterial Agents
Antineoplastic Agents
Bacteria
Cell Line, Tumor
Drug Resistance, Bacterial
Drug Synergism
Humans
Inhibitory Concentration 50
Microbial Sensitivity Tests
Porifera
Pyrrolidines
Terphenyl Compounds
Online Access:https://hdl.handle.net/10216/120275
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/120275

Internet

https://hdl.handle.net/10216/120275

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