Anti-acetylcholinesterase, antidiabetic, anti-inflammatory, antityrosinase and antixanthine oxidase activities of Moroccan propolis

Biological properties of Moroccan propolis have been scarcely studied. In the present work, the total phenols and flavonoids from 21 samples of propolis collected in different places of Morocco or 3 supplied in the market were determined, as well as the invitro capacity for inhibiting the activities...

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Bibliographic Details
Main Author: EL-GEUNDOUZ, Soukaina (author)
Other Authors: S, Azza (author), Lyoussi, Badiaa (author), Antunes, Maria Dulce (author), Faleiro, Maria Leonor (author), Miguel, Maria (author)
Format: article
Language:eng
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10400.1/9378
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/9378
Description
Summary:Biological properties of Moroccan propolis have been scarcely studied. In the present work, the total phenols and flavonoids from 21 samples of propolis collected in different places of Morocco or 3 supplied in the market were determined, as well as the invitro capacity for inhibiting the activities of acetylcholinesterase, -glucosidase, -amylase, lipoxygenase, tyrosinase, xanthine oxidase and hyaluronidase. The results showed that samples 1 (region Fez-Boulemane, Sefrou city) (IC50=0.065, 0.006, 0.020, 0.050, 0.014mgmL(-1)) and 23 (marketed) (IC50=0.018, 0.002, 0.046, 0.037, 0.008mgmL(-1)) had the best invitro capacity for inhibiting the -amylase, -glucosidase, lipoxygenase, tyrosinase and xanthine oxidase activities, respectively. A negative correlation between IC50 values and concentration of phenols, flavones and flavanones was found. These activities corresponded to the generally higher amounts of phenols and flavonoids. In the same region, propolis samples have dissimilar phenol content and enzyme inhibitory activities.