Synthesis of β-benzo[b]thienyldehydrophenylalanine derivatives by one-pot palladium-catalyzed borylation and suzuki coupling (BSC) and metal-assisted intramolecular cyclization: studies of fluorescence and antimicrobial activity

Palladium-catalyzed borylation and Suzuki coupling (BSC) in a one-pot procedure was successfully applied to the synthesis of several β-substituted dehydrophenylalanines in the benzo[b]thiophene series, with the stereochemistry of the starting materials being maintained. Bromobenzo[b]thiophenes beari...

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Bibliographic Details
Main Author: Abreu, Ana S. (author)
Other Authors: Ferreira, Paula M.T. (author), Queiroz, Maria João R.P. (author), Ferreira, Isabel C.F.R. (author), Calhelha, Ricardo C. (author), Estevinho, Leticia M. (author)
Format: article
Language:eng
Published: 2008
Subjects:
Dehydrophenylalanines
Benzothiophenes
Borylation
Suzuki coupling
Cyclization
Indoles
Fluorescence
Antimicrobial activity
Online Access:http://hdl.handle.net/10198/823
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/823

Internet

http://hdl.handle.net/10198/823

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