Mitochondrially mediated synergistic cell killing by bile acids

The accumulation of endogenous bile acids contributes to hepatocellular damage during cholestatic liver disease. To examine the controversy regarding the therapeutic use of ursodeoxycholate (UDCA) in cholestatic patients, we investigated the possible cytoprotection or synergistic effects of UDCA aga...

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Bibliographic Details
Main Author: Rolo, Anabela P. (author)
Other Authors: Palmeira, Carlos M. (author), Wallace, Kendall B. (author)
Format: article
Language:eng
Published: 2003
Subjects:
Hepatocyte
Bile acid
Ursodeoxycholate
Mitochondrial permeability transition
Cholestasis
Online Access:http://hdl.handle.net/10316/5407
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5407

Internet

http://hdl.handle.net/10316/5407

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