The role of serotonin in behavior
Serotonin (5-hydroxytryptamine, 5-HT) is a major neuromodulator linked to a disparate set of brain functions and disorders including depression and anxiety, but its fundamental roles in behavior remain a mystery. Three main theories for 5-HT function attempt to unravel how this complex neuromodulato...
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| Formato: | doctoralThesis |
| Idioma: | eng |
| Publicado em: |
2017
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| Assuntos: | |
| Texto completo: | http://hdl.handle.net/10362/20495 |
| País: | Portugal |
| Oai: | oai:run.unl.pt:10362/20495 |
| Resumo: | Serotonin (5-hydroxytryptamine, 5-HT) is a major neuromodulator linked to a disparate set of brain functions and disorders including depression and anxiety, but its fundamental roles in behavior remain a mystery. Three main theories for 5-HT function attempt to unravel how this complex neuromodulator acts in the brain: 1) behavioral inhibition, 2) sensorimotor hypothesis and 3) reward action. The vast literature in the 5-HT field is hard to reconcile and presents ambiguous results, due in part to the limitations of traditional pharmacological and physiological methods.(...) |
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